Osmosis
Renew Advanced MD
Renew Advanced MD
BENEFITS
- Improves the appearance of fine lines and wrinkles
- Skin perfecting age-fighter
- Strongest non-irritating Vitamin A
PLEASE ALLOW 1-2 WEEKS FOR PREORDER. For all gift card purchases, you will receive email confirmation after checkout.
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Osmosis MD Advanced products require a consultation before first purchase. Request the product and a SkinSkulpt team member will contact you directly. Questions: info@skinskulpt.com or (310) 770-9177.
Osmosis Renew MD is a professional-strength retinal serum built on 0.15% liposomal retinaldehyde. The MD Advanced formula pairs a high-potency retinoid with 9 collagen-targeting ingredients and 7 antioxidants, and won Favorite Retinol Serum at the 2023 Aestheticians' Choice Awards.
What Is Renew MD?
Renew MD is Osmosis's professional retinal serum for the appearance of aging skin: fine lines, loss of firmness, and uneven texture. Its active is retinaldehyde, a more direct form of vitamin A than the retinol in most over-the-counter serums. The liposomal delivery carries the active deeper while keeping it stable, and the supporting peptides and antioxidants work alongside it. As an MD Advanced product, it is stronger than a standard retinol serum, which is why it comes with a consultation.
Retinaldehyde vs Retinol: What Is the Difference?
Retinaldehyde works more directly than retinol. Every vitamin A derivative must convert to retinoic acid to act on the skin. Retinol takes two conversion steps; retinaldehyde takes one. That single step makes retinaldehyde more efficient than retinol at a comparable tolerance, delivering visible results without the harshness of prescription retinoic acid. Renew MD uses retinaldehyde at 0.15%, a meaningful concentration for a leave-on serum.
What Is in Renew MD?
Renew MD surrounds its retinoid with collagen and antioxidant support.
- Retinaldehyde (0.15%) is the active retinoid, one step from retinoic acid
- Peptides (caprooyl tetrapeptide-3, palmitoyl tripeptide-38) support collagen
- Niacinamide strengthens the barrier and evens tone
- Beta-glucan and sodium hyaluronate hydrate and calm
- Thioctic (alpha-lipoic) acid, fulvic acid, and chlorella provide antioxidant defence
The serum contains botanical aromatics and is not fragrance-free.
Who It Is For
Choose Renew MD if your priority is the appearance of aging: fine lines, firmness, and texture, and if you want a professional-strength retinoid guided by a consultation. It suits skin ready for an active retinoid. It is not for use during pregnancy or breastfeeding, when retinoids are best avoided, which the consultation will confirm.
For a gentler starting point, or for hydration rather than active renewal, the Serums range covers lower-intensity options.
How to Buy: Consultation First
Renew MD is part of the Osmosis MD Advanced collection, sold only through trained professionals. SkinSkulpt arranges a short consultation before your first order, which matters more for a retinoid than most products: strength, frequency, and how to introduce it depend on your skin and current routine. Request the product here and a team member will confirm the fit and complete the purchase.
How to Use Renew MD
On clean skin, apply one to two pumps in the evening to start, following the consultation's guidance on frequency. Introduce a retinoid gradually, a few nights a week, building up as the skin adjusts. Always wear SPF the following day, because retinoids increase sun sensitivity. Browse the full Osmosis range for products that layer with it.
FAQs
What is the difference between retinaldehyde and retinol?
Retinaldehyde is one conversion step from active retinoic acid, while retinol takes two steps. This makes retinaldehyde more direct and efficient than retinol at comparable tolerance, without the irritation of prescription retinoids. Renew MD uses 0.15% liposomal retinaldehyde, a professional-strength concentration in a stabilised delivery system.
Why does Renew MD require a consultation?
Osmosis sells its MD Advanced collection only through trained professionals, and a retinoid especially benefits from guidance. The consultation confirms the right strength and frequency for your skin, how to introduce it without irritation, and whether it suits your current routine. Request the product and a SkinSkulpt team member will reach out.
Can I use Renew MD during the day?
Renew MD can be applied morning or evening, though many start with evening use while the skin adjusts. Whenever you apply it, wear SPF the following day, because all retinoids increase sun sensitivity. Introduce it gradually, a few nights weekly, and build up as tolerated, following your consultation's guidance.
HOW TO USE
On clean skin, apply 1-2 pumps in the evening.
WHERE
Apply to face and neck
WHEN
Use in the evening

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